10 Key publications

1. Helicobacter pylori, homologous recombination genes and gastric cancer
   Usui Y, Taniyama Y, Endo M, Koyanagi Y, Kasugai Y, Oze I, Ito H, Imoto I, Tanaka T, Tajika M, Niwa Y, Iwasaki Y, Aoi T, Hakozaki N, Takata S, Suzuki K, Terao C, Hatakeyama M, Hirata M, Sugano K, Yoshida T, Kamatani Y, Nakagawa H, Matsuda K, Murakami Y, Spurdle A, Matsuo K, Momozawa Y; N Engl J Med 388:1181-1190, 2023
   DOI: 10.1056/NEJMoa2211807 　 日本語解説: 理研プレスリリース
2. Expansion of Cancer Risk Profile for BRCA1 and BRCA2 Pathogenic Variants
   Momozawa Y, Sasai R, Usui Y, Shiraishi K, Iwasaki Y, Taniyama Y, Parsons M T., Mizukami K, Sekine Y, Hirata M, Kamatani Y, Endo M, Inai C, Takata S, Ito H, Kohno T, Matsuda K, Nakamura S, Sugano K, Yoshida T, Nakagawa H, Matsuo K, Murakami Y, Spurdle A B., Kubo M; JAMA Oncol 8:871-878, 2022
   DOI: 10.1001/jamaoncol.2022.0476 　 日本語解説: 理研プレスリリース
3. Combined inhibition of XIAP and BCL2 drives maximal therapeutic efficacy in genetically diverse aggressive acute myeloid leukemia
   Hashimoto M, Saito Y, Nakagawa R, Ogahara I, Takagi S, Takata S, Amitani H, Endo M, Yuki H, Ramilowski J A., Severin J, Manabe R, Watanabe T, Ozaki K, Kaneko A, Kajita H, Fujiki S, Sato K, Honma T, Uchida N, Fukami T, Okazaki Y, Ohara O, Shultz L D., Yamada M, Taniguchi S, Vyas P, De Hoon M, Momozawa Y, Ishikawa F; Nat Cancer 2:340–356, 2021
   DOI: 10.1038/s43018-021-00177-w 　 日本語解説: 理研プレスリリース
4. Combined landscape of single-nucleotide variants and copy number alterations in clonal hematopoiesis
   Saiki R, Momozawa Y, Nannya Y, Nakagawa M M., Ochi Y, Yoshizato T, Terao C, Kuroda Y, Shiraishi Y, Chiba K, Tanaka H, Niida A, Imoto S, Matsuda K, Morisaki T, Murakami Y, Kamatani Y, Matsuda S, Kubo M, Miyano S, Makishima H, Ogawa S; Nat Med 27:1239–1249, 2021
   DOI: 10.1038/s41591-021-01411-9 　 日本語解説: 理研プレスリリース
5. Genetic characterization of pancreatic cancer patients and prediction of carrier status of germline pathogenic variants in cancer-predisposing genes.
   Mizukami K, Iwasaki Y, Kawakami E, Hirata M, Kamatani Y, Matsuda K, Endo M, Sugano K, Yoshida T, Murakami Y, Nakagawa H, Spurdle A B., Momozawa Y; EBioMedicine 60:103033, 2020
   DOI: 10.1016/j.ebiom.2020.103033 　 日本語解説: 理研プレスリリース
6. Germline pathogenic variants of 11 breast cancer genes in 7,051 Japanese patients and 11,241 controls.
   Momozawa Y, Iwasaki Y, Parsons MT, Kamatani Y, Takahashi A, Tamura C, Katagiri T, Yoshida T, Nakamura S, Sugano K, Miki Y, Hirata M, Matsuda K, Spurdle A B., Kubo M; Nat Commun 9:4083, 2018
   DOI: 10.1038/s41467-018-06581-8 　 日本語解説: 理研プレスリリース
7. Low-frequency coding variants in CETP and CFB are associated with susceptibility of exudative age-related macular degeneration in the Japanese population.
   Momozawa Y, Akiyama M, Kamatani Y, Arakawa S, Yasuda M, Yoshida S, Oshima Y, Mori R, Tanaka K, Mori K, Inoue S, Terasaki H, Yasuma T, Honda S, Miki A, Inoue M, Fujisawa K, Takahashi K, Yasukawa T, Yanagi Y, Kadonosono K, Sonoda K, Ishibashi T, Takahashi A, Kubo M; Hum Mol Genet 25:5027-5034, 2016
   DOI: 10.1093/hmg/ddw335
8. Genome-wide association study identifies two susceptibility loci for exudative age-related macular degeneration in the Japanese population.
   Arakawa S, Takahashi A, Ashikawa K, Hosono N, Aoi T, Yasuda M, Oshima Y, Yoshida S, Enaida H, Tsuchihashi T, Mori K, Honda S, Negi A, Arakawa A, Kadonosono K, Kiyohara Y, Kamatani N, Nakamura Y, Ishibashi T, Kubo M; Nat Genet 43:1001-4, 2011
   DOI: 10.1038/ng.938
9. A nonsynonymous SNP in PRKCH (protein kinase C eta) increases the risk of cerebral infarction.
   Kubo M, Hata J, Ninomiya T, Matsuda K, Yonemoto K, Nakano T, Matsushita T, Yamazaki K, Ohnishi Y, Saito S, Kitazono T, Ibayashi S, Sueishi K, Iida M, Nakamura Y, Kiyohara Y; Nat Genet 39:212-7, 2007
   DOI: 10.1038/ng1945
10. A haplotype map of the human genome.
    The International HapMap Consortium; Nature 437:1299-320, 2005
    DOI: 10.1038/nature04226