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News Releases 2021


2021/7/30 Dr. Kenya Honda

腸内細菌から産生される健康長寿に関わる胆汁酸 百寿者のマイクロバイオームで増加する新たな胆汁酸の生合成経路

Novel bile acid biosynthetic pathways are enriched in the microbiome of centenarians. Nature, doi: 10.1038/s41586-021-03832-5

2021/7/15 Dr. Hiroshi Ohno


2021/3/18 Dr. Hiroshi Ohno, Dr. Atsushi Miyawaki, Dr. Ken Shirasu and Dr. Yasunori Ichihashi received RIKEN EIHO Award (RIKEN Sginificant Achievement Award) and Dr. Takayuki Motoyama received RIKEN BAIHO Award (RIKEN Excellent Achievement Award)


2021/3/17 Dr. Atsushi Miyawaki received Japan Academy Medal

宮脇 敦史チームリーダー、神谷 勇治名誉研究員が日本学士院賞を受賞

2021/March Dr. Shunji Takahashi's interview is published in the March issue of RIKEN NEWS


2021/January Dr. Aki Minoda's interview is published in the Janury issue of RIKEN NEWS


News Releases 2020


2020/December Dr. Yasunori Ichihashi's interview is published in the December issue of RIKEN NEWS


2020/November Dr. Ken Shirasu's interview is published in the November issue of RIKEN NEWS


2020/9/3 Dr. Ken Shirasu


Parasitic plants attack crops when defending themselves from microbes

2020/8/27 Dr. Hiroshi Ohno


Tag team gut bacteria worsen symptoms of multiple sclerosis

2020/July Dr. Makoto Hayashi's interview is published in the July issue of RIKEN NEWS


2020/6/9 Collaboration Dr. Yasunori Ichihashi, Dr. Ken Shirasu and Dr. Jun Kikuchi


Using multiomics in an agricultural field, scientists discover that organic nitrogen plays a key role in plant growth

2020/4/22 Dr. Hiroshi Ohno


CD8+ regulatory T cells are critical in prevention of autoimmune-mediated diabetes

2020/2/7 Dr. Makoto Hayashi

A single gene controls root nodulation and lateral root growthーA gene involved in the development of lateral roots is found to play a role in the formation of nitrogen-fixing nodules

News Releases 2019


2019/11/22 Dr. Makoto Hayashi


Recrutement of a lateral root developmental pathway into root nodule formation of legumes

2019/Fall Dr. Ken Shirasu's interview is published in the fall issue of RIKEN RESEARCH


2019/9/13 Dr. Ken Shirasu


Genome Sequence of Striga asiatica Provides Insight into the Evolution of Plant Parasitism. Current Biology, doi:10.1016/j.cub.2019.07.086

2019/9/2 Dr. Kiminori Toyooka, Dr. Masayuki Amagai

3D in vivo imaging of the keratin filament network in the mouse stratum granulosum reveals profilaggrin-dependent regulation of keratin bundling. Journal of Dermatological Science, doi:10.1016/j.jdermsci.2019.04.006

2019/July Dr. Sidonia Fagarasan's interview is published in the July issue of RIKEN NEWS


2019/7/10 Dr. Moriya Ohkuma


Isolation and characterization of a thermophilic sulfur- and iron-reducing thaumarchaeote from a terrestrial acidic hot spring. The ISME Journal, doi: 10.1038/s41396-019-0447-3

2019/1/28 Dr. Hiroyuki Osada


Induction of Nectriapyrone Biosynthesis in the Rice Blast Fungus Pyricularia oryzae by Disturbance of the Two‐Component Signal Transduction System. ChemBioChem, doi:10.1002/cbic.201800620

2019/1/24 Dr. Kenya Honda

健常者から単離 感染抵抗性や抗腫瘍効果を高める腸内細菌株

A defined commensal consortium elicits CD8 T cells and anti-cancer immunity. Nature, doi:10.1038/s41586-019-0878-z

News Releases 2018


2018/November Dr. Shigehiro Kuraku author interview by Nature Japan

Nature Ecology & Evolution 著者インタビュー『工樂樹洋氏:サメのゲノムが挑む、進化と自然の謎』

2018/11/29 Dr. Kenya Honda, Dr. Ken shirasu and Dr. Kazuki Saito were selected as Highly Cited Researchers

Clarivate Analytics Highly Cited Researchers

2018/11/2 Dr. Kazuki Saito received the Medal of Honor with Purple Ribbon

The government of Japan awarded Dr. Kazuki Saito the Medal of Honor with Purple Ribbon which is awarded to individuals who have contributed to academic and artistic developments, improvements and accomplishment.


Decorations and Medals in Japan (Cabinet Office, Government of Japan)

2018/November Dr.Shigehiro Kuraku's interview is published in the November issue of RIKEN NEWS


2018/10/19 Dr. Hiroyuki Osada


Structures and Synthesis of Hitoyopodins: Bioactive Aromatic Sesquiterpenoids Produced by the Mushroom Coprinopsis cinerea. Organic Letters, doi: 10.1021/acs.orglett.8b02788

2018/10/9 Dr. Shigehiro Kuraku


Whole genomes of shark species decodedーGetting a grip on the slow but unique evolution of sharksー

2018/September Dr. Arno Germond received the Early Research in Biophysics Award of The Biophysical Society of Japan


2018/September Dr.Miyawaki's interview is published in the September issue of RIKEN NEWS


2018/07/24 Dr. Sidonia Fagarasan

IgAは腸内細菌間の相互作用を誘導する (RIKEN Press Release)

IgA regulates the composition and metabolic function of gut microbiota by promoting symbiosis between bacteria. Journal of Experimental Medicine, doi: 10.1084/jem.2018042

2018/07/17 Dr. Arno Germond

非染色・非侵襲・短時間で細菌を判別する光技術 (RIKEN Press Release)

Raman spectral signature reflects transcriptomic features of antibiotic resistance. Communications Biology, doi: 10.1038/s42003-018-0093-8

2018/06/27 It's World Microbiome Day! APC Microbiome Ireland developed the day. Find more details about the World Microbiome Day, please go to the following page!

World Microbiome Day Website

2018/April Dr. Moriya Ohkuma and Dr. Jun Kikuchi's interviews are published in the April issue of RIKEN NEWS.


2018/4/17 Dr. Hiroshi Ohno received the Commendation for Science and Technology by the Minister of Education, Culture, Sports, Science and Technology. 


2018/4/1 Dr. Shirasu group with Dr. Ichihashi team signed a collaborative research agreement with Daichi no Inochi Co., LTD(株式会社大地のいのち) . The purpose is to verify the effects of microbial materials in agriculture

Daichi no Inochi Co., LTD (株式会社大地のいのち) Website

2018/3/28 Dr. Ichihashi’s collaboration team revealed the mechanism how soil solarization promotes the crop yield. (日本農業新聞2018年3月28日)
2018/2/23 Dr. Atsushi Miyawaki team's paper has been published in Science

脳の深部を非侵襲的に観察できる人工生物発光システムAkaBLI (RIKEN Press Release)

Single-cell bioluminescence imaging of deep tissue in freely moving animals. Science, doi:10.1126/science.aaq1067

News Releases 2017


2017/11/2  Dr. Atsushi Miyawaki received the Medal of Honor with Purple Ribbon

The government of Japan awarded Dr. Atsushi Miyawaki the Medal of Honor with Purple Ribbon which is awarded to individuals who have contributed to academic and artistic developments, improvements and accomplishment.

宮脇敦史副センター長が紫綬褒章を受章 (RIKEN)

Decorations and Medals in Japan (Cabinet Office, Government of Japan)

2017/10/25 Dr. Jianshi Jin from Laboratory for Integrative Omics(Unit leader: Dr. Katsuyuki Shiroguchi) received Cold Spring Harbor Asia Fellowship Award in Tumor Immunology & Immunotherapy

Cold Spring Harbor Asia

2017/10/20  Dr. Kenya Honda & Dr. Masahira Hattori's collaborative research team


Ectopic colonization of oral bacteria in the intestine drives TH1 cell induction and inflammation. Science, doi:10.1126/science.aan4526

2017/10/19  Dr. Katsuyuki Shiroguchi's unit

DNA分子バーコード法の新機能 (RIKEN Press Release)

The efficacy and further functional advantages of random-base molecular barcodes for absolute and digital quantification of nucleic acid molecules. Scientific Reports, doi: 10.1038/s41598-017-13529-3

2017/10/6  Dr. Hiroyuki Osada's team

Identification of production control factors for tenuazonic acid (RIKEN CSRS Press Release)

Regulatory Mechanism of Mycotoxin Tenuazonic Acid Production in Pyricularia oryzae. ACS Chemical Biology, doi: 10.1021/acschembio.7b00353

2017/7/25  Dr. Hiroyuki Osada's international collaborative research team

化合物の標的機能を決定するツールを開発 (RIKEN Press Release)

Functional Annotation of Chemical Libraries across Diverse Biological Processes. Nature Chemical Biology, doi: 10.1038/nchembio.2436

News Report 7


2019/10/7, 10

Sequel II training @Yokohama RIKEN

There was a Sequel II training at Yokohama RIKEN.  

Preparation of samples
Sequel II system
Seminar by Pacific Biosciences

Photos from Sequel II Training


News Report 6



Sequel II System has been introduced.

"Sequel II System" has been introduced to RIKEN Yokohama. It has been installed next to Sequel. The read lengths is about eight times longer than original system!

Photo of PacBio Sequel II and I

PacBio Sequel II and original



News Report 5


2019/4/18-19, 6/17-18

Cell Sorter training @Yokohama RIKEN

The FACS Aria Fusion cell sorter has been introduced and there was a training for using the machine. 

Cell Sorter training@Yokohama RIKEN

The training was held by BD Biosciences


News Report 4



PacBio Sequel training @Yokohama RIKEN

PacBio Sequel training was held for five days. The schedule of training included from sample preparation untill sequencing. During the training, there was also a bioinformatics seminar by PacBio Asia. I hope the training was fruitful for everyone. Attendees were from a variety of research fields in symbiology so it was also a great opportunity to get to know each other. 

Preparation of samples
Seminar by TOMY digital biology
Touching a screen of PacBio

Photos from PacBio Training


News Report 3



PacBio Sequel training seminar @Yokohama RIKEN

There was a PacBio Sequel training seminar held by Dr. Miwako Kitazume from TOMY digital biology on 1st of February. 

Photo of PacBio Sequel Training Seminar

Dr. Miwako Kitazume from TOMY digital biology



News Report 2



PacBio Sequel system has been introduced.

"PacBio Sequel system" has been introduced to RIKEN Yokohama by Microbiome Research Team.
The team leader is Dr. Masahira Hattori

Photo of PacBio Sequel system introduction

PacBio Sequel system



News Report 1 



Zeiss LSM880 Airyscan has been introduced.

"Confocal Laser Scanning Microscope Zeiss LSM880 with Airyscan FAST-mode" has been introduced to RIKEN YokohamaCSRS Microscopy Room by Mass Spectrometry and Microscopy Unit.
The unit leader is Dr. Kiminori Toyooka

Photo of Zeiss LSM880 Airyscan introduction
Photo of technical training of Zeiss LSM880 Airyscan

Technical training

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