Integrated Symbiology
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About iSYM

Integrated Symbiology (iSYM) is an interdisciplinary research program at RIKEN, studying organism-organism interactions. High biological diversity, which is built on numerous organism-organism interactions, ensures natural sustainability for all life forms, including us. 
We aim to understand how organisms interact with each other in the molecular level, revealing novel communication tools and controlling strategies developed by various life forms.

Recent Event

Symbiology Workshop 2019 & RIKEN-JSS Joint Symposium

Date: 2019 November 18-19
Venue: Yokohama RIKEN, Lecture Hall
Hosts: iSYM, Biology of Symbiosis and Japan Symbiology Society


Symbiology Workshop 2019 group photo

Recent News Releases


2019/11/22 Dr. Makoto Hayashi


Recrutement of a lateral root developmental pathway into root nodule formation of legumes

2019/Autumn Dr. Ken Shirasu's interview is published in the fall issue of RIKEN RESEARCH


2019/9/13 Dr. Ken Shirasu


Genome Sequence of Striga asiatica Provides Insight into the Evolution of Plant Parasitism. Current Biology, doi:10.1016/j.cub.2019.07.086

2019/8/30 Dr. Kiminori Toyooka, Dr. Masayuki Amagai

3D in vivo imaging of the keratin filament network in the mouse stratum granulosum reveals profilaggrin-dependent regulation of keratin bundling. Journal of Dermatological Science, doi:10.1016/j.jdermsci.2019.04.006

2019/July Dr. Sidonia Fagarasan's interview is published in the July issue of RIKEN NEWS


2019/7/10 Dr. Moriya Ohkuma


Isolation and characterization of a thermophilic sulfur- and iron-reducing thaumarchaeote from a terrestrial acidic hot spring. The ISME Journal, doi: 10.1038/s41396-019-0447-3

2019/1/28 Dr. Hiroyuki Osada

かびの二次代謝活性化-ネクトリアピロン類の生合成遺伝子を同定-(RIKEN Press Release)

Induction of Nectriapyrone Biosynthesis in the Rice Blast Fungus Pyricularia oryzae by Disturbance of the Two‐Component Signal Transduction System. ChemBioChem, doi:10.1002/cbic.201800620

2019/1/24 Dr. Kenya Honda

健常者から単離 感染抵抗性や抗腫瘍効果を高める腸内細菌株

A defined commensal consortium elicits CD8 T cells and anti-cancer immunity. Nature, doi:10.1038/s41586-019-0878-z


Featured News Report

Sequel II System has been introduced!

"Sequel II System" has been introduced to RIKEN Yokohama. It has been installed next to Sequel. The read lengths is about eight times longer than original system!

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