2018年
Kato, T., Yamazaki, K., Nakajima, M., Date, Y., Kikuchi, J., Hase, K.,
Ohno, H., Yamazaki, K. Oral administration of Porphyromonas gingivalis
Alters the Gut Microbiome and Serum Metabolome.
mSphere.17;3(5). pil: e00460-18, 2018
Kanaya, T., Sakakibara, S., Jinnohara, T., Hachisuka, M., Tachibana, N.,
Hidano , S., Kobayashi, T., Kimura, S., Iwanaga, T., Nakagawa, T., Katsuno,
T., Kato, N., Akiyama, T., Sato, T., Williams, I. R., Ohno, H. Development
of intestinal M cells and follicle-associated epithelium is regulated by
TRAF6-mediated NF- kappa B signaling.
J. Exp. Med.215:501-519, 2018
2017年
Takayasu, L., Suda, W., Watanabe, E., Fukuda, S., Takanashi, K., Ohno,
H., Takayasu, M., Takayasu, H., Hattori, M. A 3-dimensional mathematical
model of microbial proliferation that generates the characteristic cumulative
relative abundance distributions in gut microbiomes.
PLoS ONE12(8):e0180863, 2017
Lye HS, Kato T, Low WY, Taylor TD, Prakash T, Lew LC, Ohno H, *Liong MT.
Lactobacillus fermentum FTDC 8312 combats hypercholesterolemia via alteration
of gut microbiota.
J. Biotechnol.262: 75-83, 2017
Yanagihara S, Kanaya T, Fukuda S, Nakato G, Hanazato M, Wu XR, Yamamoto
N, Ohno H. Uromodulin-SlpA binding dictates Lactobacillus acidophilus uptake
by intestinal epithelial M cells.
Int. Immunol.29: 357-363, 2017
Nakajima A, Kaga N, Nakanishi Y, Ohno H, Miyamoto J, Kimura I, Hori S,
Sasaki T, Hiramatsu K, Okumura K, Miyake S, Habu S, Watanabe S. Maternal
High Fiber Diet during Pregnancy and Lactation Influences Regulatory T
Cell Differentiation in Offspring in Mice.
J. Immunol.199: 3516-3524, 2017
Date Y, Ebisawa M, Fukuda S, Shima H, Obata Y, Takahashi D, Kato T, Hanazato
M, Nakato G, Williams IR, Hase K, Ohno H. NALT M cells are important for
immune induction for the common mucosal immune system.
Int. Immunol.29: 471-478, 2017
Jinnohara, T., Kanaya, T., Hase, K., Sakakibara, S., Kato, T., Tachibana,
N., Sasaki, T., Hashimoto, Y., Sato, T., Watarai, H., Kunisawa, J., Shiba.ta,
N, Williams, I. R., Kiyono, H., Ohno , H. IL-22BP dictates characteristics
of Peyer's patch follicle-associated epithelium for antigen uptake.
J. Exp. Med.;214(6):1607-1618 .2017
Shimokawa, C., Kanaya, T., Hachisuka, M., Ishiwata, K., Hisaeda, H., Kurashima,
Y., Kiyono, H., Yoshimoto, T., Kaisho, T., Ohno, H. Mast cells are crucial
for induction of group 2 innate lymphoid cells and clearance of helminth
infections.
Immunity46(5):863-874.e4. 2017
2016年
Kimura S, Yamashita M, Yamakami-Kimura M, Sato Y, Yamagata A, Kobashigawa
Y, Inagaki F, Amada T, Hase K, Iwanaga T, Ohno H , Fukai S. Distinct Roles
for the N- and C-terminal Regions of M-Sec in Plasma Membrane Deformation
during Tunneling Nanotube Formation.
Sci Rep .2016 Sep 15;6:33548. doi: 10.1038/srep33548.
Ohashi W, Kimura S, Iwanaga T, Furusawa Y, Irie T, Izumi H, Watanabe T,
Hijikata A, Hara T, Ohara O, Koseki H, Sato T, Robine S, Mori H, Hattori
Y, Watarai H, Mishima K, Ohno H , Hase K , Fukada T. Zinc Transporter SLC39A7/ZIP7
Promotes Intestinal Epithelial Self-Renewal by Resolving ER Stress.
PLoS Genet .2016 Oct 13;12(10):e1006349. doi: 10.1371/journal.pgen.1006349. eCollection
2016 Oct.
Okai S, Usui F, Yokota S, Hori-I Y, Hasegawa M, Nakamura T, Kurosawa M,
Okada S, Yamamoto K, Nishiyama E, Mori H, Yamada T, Kurokawa K, Matsumoto
S, Nanno M, Naito T, Watanabe Y, Kato T, Miyauchi E, Ohno H , Shinkura
R. High-affinity monoclonal IgA regulates gut microbiota and prevents colitis
in mice.
Nat Microbiol .2016 Jul 4;1(9):16103. doi: 10.1038/nmicrobiol.2016.103.
Yasuda T, Fukada T , Nishida K, Nakayama M, Matsuda M, Miura I, Dainichi
T, Fukuda S, Kabashima K, Nakaoka S, Bin BH, Kubo M, Ohno H , Hasegawa
T, Ohara O, Koseki H, Wakana S, Yoshida H. Hyperactivation of JAK1 tyrosine
kinase induces stepwise, progressive pruritic dermatitis.
J Clin Invest.2016 Jun 1;126(6):2064-76. doi: 10.1172/JCI82887. Epub 2016 Apr 25.
Matsuda Y, Kato T, Takahashi N, Nakajima M, Arimatsu K, Minagawa T, Sato
K, Ohno H , Yamazaki K.Ligature-induced periodontitis in mice induces elevated
levels of circulating interleukin-6 but shows only weak effects on adipose
and liver tissues.
J Periodontal Res .2016 Oct;51(5):639-46. doi: 10.1111/jre.12344. Epub 2015 Dec 15.
Hayashi R, Tsuchiya K, Fukushima K, Horita N, Hibiya S, Kitagaki K, Negi
M, Itoh E, Akashi T, Eishi Y, Okada E, Araki A, Ohtsuka K, Fukuda S , Ohno
H , Okamoto R, Nakamura T, Tanaka S, Chayama K, Watanabe M. Reduced Human
α-defensin 6 in Noninflamed Jejunal Tissue of Patients with Crohn's Disease.
Inflamm Bowel Dis .2016 May;22(5):1119-28. doi: 10.1097/MIB.0000000000000707.
Nakato G, Hase K, Sato T, Kimura S, Sakakibara S, Sugiyama M, Obata Y,
Hanazato M, Iwanaga T, Ohno H . Epithelium-Intrinsic MicroRNAs Contribute
to Mucosal Immune Homeostasis by Promoting M-Cell Maturation.
PLoS One .2016 Mar 1;11(3):e0150379. doi: 10.1371/journal.pone.0150379. eCollection
2016.
Hashimoto M, Bhuyan F, Hiyoshi M, Noyori O, Nasser H, Miyazaki M, Saito
T, Kondoh Y, Osada H, Kimura S, Hase K, Ohno H , Suzu S. Potential Role
of the Formation of Tunneling Nanotubes in HIV-1 Spread in Macrophages.
J Immunol .2016 Feb 15;196(4):1832-41. doi: 10.4049/jimmunol.1500845. Epub 2016 Jan
15.
2015年
Hurst LD, Ghanbarian AT, Forrest AR; FANTOM consortium., Huminiecki L.
The Constrained Maximal Expression Level Owing to Haploidy Shapes Gene
Content on the Mammalian X Chromosome.
PLoS Biol. 2015 Dec 18;13(12):e1002315. doi: 10.1371/journal.pbio.1002315. eCollection
2015 Dec.
Carbajo D, Magi S, Itoh M, Kawaji H, Lassmann T, Arner E, Forrest AR, Carninci
P, Hayashizaki Y, Daub CO; FANTOM consortium., Okada-Hatakeyama M, Mar
JC. Application of Gene Expression Trajectories Initiated from ErbB Receptor
Activation Highlights the Dynamics of Divergent Promoter Usage.
PLoS One.2015 Dec 14;10(12):e0144176. doi: 10.1371/journal.pone.0144176. eCollection
2015.
Atarashi K, Tanoue T, Ando M, Kamada N, Nagano Y, Narushima S, Suda W,
Imaoka A, Setoyama H, Nagamori T, Ishikawa E, Shima T, Hara T, Kado S,
Jinnohara T, Ohno H , Kondo T, Toyooka K, Watanabe E, Yokoyama S, Tokoro
S, Mori H, Noguchi Y, Morita H, Ivanov II, Sugiyama T, Nunez G, Camp JG,
Hattori M, Umesaki Y, Honda K. Th17 Cell Induction by Adhesion of Microbes
to Intestinal Epithelial Cells.
Cell.2015 Oct 8;163(2):367-80. doi: 10.1016/j.cell.2015.08.058. Epub 2015 Sep
24.
Taniguchi T, Miyauchi E, Nakamura S, Hirai M, Suzue K, Imai T, Nomura T,
Handa T, Okada H, Shimokawa C, Onishi R, Olia A, Hirata J, Tomita H, Ohno
H , Horii T, Hisaeda H. Plasmodium berghei ANKA causes intestinal malaria
associated with dysbiosis.
Sci Rep.2015 Oct 27;5:15699. doi: 10.1038/srep15699.
Sugahara H, Odamaki T, Fukuda S, Kato T, Xiao JZ, Abe F, Kikuchi J, Ohno
H.Probiotic Bifidobacterium longum alters gut luminal metabolism through
modification of the gut microbial community.Sci Rep.2015 Aug 28;5:13548. doi: 10.1038/srep13548.
Nakato G, Hase K, Ohno H . Distinct microRNA expression profiles in follicle-associated
epithelium and villous epithelium.Genom Data. 2015 Jul 15;5:388-90. doi: 10.1016/j.gdata.2015.07.011. eCollection 2015
Sep.
Nakajima M, Arimatsu K, Kato T, Matsuda Y, Minagawa T, Takahashi N, Ohno
H , Yamazaki K. Oral Administration of P. gingivalis Induces Dysbiosis
of Gut Microbiota and Impaired Barrier Function Leading to Dissemination
of Enterobacteria to the Liver.
PLoS One .2015 Jul 28;10(7):e0134234. doi: 10.1371/journal.pone.0134234. eCollection
2015.
Nishida A, Miyamoto H, Horiuchi S, Watanabe R, Morita H, Fukuda S, Ohno
H , Ichinose S, Miyamoto H, Kodama H.Bacillus hisashii sp. nov., isolated
from the caeca of gnotobiotic mice fed with thermophile-fermented compost.
Int J Syst Evol Microbiol.2015 Aug 12. doi: 10.1099/ijsem.0.000516. [Epub ahead of print]
Yoshihara M, Ohmiya H, Hara S, Kawasaki S; FANTOM consortium., Hayashizaki
Y, Itoh M, Kawaji H, Tsujikawa M, Nishida K.Discovery of molecular markers
to discriminate corneal endothelial cells in the human body.
PLoS One.2015 Mar 25;10(3):e0117581. doi: 10.1371/journal.pone.0117581. eCollection
2015.
Matsumura T, Sugawara Y, Yutani M, Amatsu S, Yagita H, Kohda T, Fukuoka
S, Nakamura Y, Fukuda S, Hase K, Ohno H , Fujinaga Y. Botulinum toxin A
complex exploits intestinal M cells to enter the host and exert neurotoxicity.
Nat Commun.2015 Feb 17;6:6255. doi: 10.1038/ncomms7255.
Kimura S, Yamakami-Kimura M, Obata Y, Hase K, Kitamura H, Ohno H , Iwanaga
T. Visualization of the entire differentiation process of murine M cells:
suppression of their maturation in cecal patches.
Mucosal Immunol.2015 May;8(3):650-60. doi: 10.1038/mi.2014.99. Epub 2014 Oct 22
Liang C; FANTOM Consortium., Forrest AR, Wagner GP.The statistical geometry
of transcriptome divergence in cell-type evolution and cancer.
Nat Commun.2015 Jan 14;6:6066. doi: 10.1038/ncomms7066.
2014年
Yanagihara S, Goto H, Hirota T, Fukuda S, Ohno H , Yamamoto N. Lactobacillus
acidophilus L-92 Cells Activate Expression of Immunomodulatory Genes in
THP-1 Cells.
Biosci Microbiota Food Health.2014;33(4):157-64. doi: 10.12938/bmfh.33.157. Epub 2014 Aug 1.
Obata Y, Kimura S, Nakato G, Iizuka K, Miyagawa Y, Nakamura Y, Furusawa
Y, Sugiyama M, Suzuki K, Ebisawa M, Fujimura Y, Yoshida H, Iwanaga T, Hase
K, Ohno H . Epithelial-stromal interaction via Notch signaling is essential
for the full maturation of gut-associated lymphoid tissues.
EMBO Rep.2014 Dec;15(12):1297-304. doi: 10.15252/embr.201438942. Epub 2014 Nov 5.
Obata Y, Furusawa Y, Endo TA, Sharif J, Takahashi D, Atarashi K, Nakayama
M, Onawa S, Fujimura Y, Takahashi M, Ikawa T, Otsubo T, Kawamura YI, Dohi
T, Tajima S, Masumoto H, Ohara O, Honda K, Hori S, Ohno H , Koseki H, Hase
K. The epigenetic regulator Uhrf1 facilitates the proliferation and maturation
of colonic regulatory T cells.
Nat Immunol.2014 Jun;15(6):571-9. doi: 10.1038/ni.2886. Epub 2014 Apr 28.
Honjo K, Kubagawa Y, Suzuki Y, Takagi M, Ohno H , Bucy RP, Izui S, Kubagawa
H. Enhanced auto-antibody production and Mott cell formation in FcμR-deficient
autoimmune mice.
Int Immunol.2014 Dec;26(12):659-72. doi: 10.1093/intimm/dxu070. Epub 2014 Jul 3.
Hasegawa Y, Tang D, Takahashi N, Hayashizaki Y, Forrest AR; FANTOM Consortium.,
Suzuki H. CCL2 enhances pluripotency of human induced pluripotent stem
cells by activating hypoxia related genes. Sci Rep . 2014 Jun 24;4:5228.
doi: 10.1038/srep05228. Erratum in:
Sci Rep.2014;4:6385.
Bubier JA, Jay JJ, Baker CL, Bergeson SE, Ohno H , Metten P, Crabbe JC,
Chesler EJ. Identification of a QTL in Mus musculus for alcohol preference,
withdrawal, and Ap3m2 expression using integrative functional genomics
and precision genetics.
Genetics .2014 Aug;197(4):1377-93. doi: 10.1534/genetics.114.166165. Epub 2014 Jun
11.
Shima H, Watanabe T, Fukuda S , Fukuoka S, Ohara O, Ohno H . A novel mucosal
vaccine targeting Peyer's patch M cells induces protective antigen-specific
IgA responses.
Int Immunol .2014 Nov;26(11):619-25. doi: 10.1093/intimm/dxu061. Epub 2014 Jun 7.
Furusawa Y, Endo TA, Obata Y, Ohara O, Ohno H , Hase K . Pitfalls in global
normalization of ChIP-seq data in CD4(+) T cells treated with butyrate:
A possible solution strategy.
Genom Data. 2014 Jun 27;2:176-80. doi: 10.1016/j.gdata.2014.06.018. eCollection 2014
Dec.
Kato T, Fukuda S , Fujiwara A, Suda W, Hattori M, Kikuchi J, Ohno H . Multiple
omics uncovers host-gut microbial mutualism during prebiotic fructooligosaccharide
supplementation.
DNA Res. 2014 Oct;21(5):469-80. doi: 10.1093/dnares/dsu013. Epub 2014 May 19.
Obata Y, Kimura S, Nakato G, Iizuka K, Miyagawa Y, Nakamura Y, Furusawa
Y, Sugiyama M, Suzuki K, Ebisawa M, Fujimura Y, Yoshida H, Iwanaga T, Hase
K , Ohno H . Epithelial-stromal interaction via Notch signaling is essential
for the full maturation of gut-associated lymphoid tissues.
EMBO Rep .2014 Dec;15(12):1297-304. doi: 10.15252/embr.201438942. Epub 2014 Nov 5.
Nagasawa Y, Iio K, Fukuda S , Date Y, Iwatani H, Yamamoto R, Horii A, Inohara
H, Imai E, Nakanishi T, Ohno H , Rakugi H, Isaka Y. Periodontal disease
bacteria specific to tonsil in IgA nephropathy patients predicts the remission
by the treatment.PLoS One. 2014 Jan 28;9(1):e81636. doi: 10.1371/journal.pone.0081636. eCollection
2014.
Date Y, Nakanishi Y, Fukuda S, Nuijima Y, Kato T, Umehara M, Ohno H , Kikuchi
J. In vitro evaluation method for screening of candidate prebiotic foods.
Food Chem .2014;152:251-60. doi: 10.1016/j.foodchem.2013.11.126. Epub 2013 Dec 1.
Hanazato M, Nakato G, Nishikawa F, Hase K, Nishikawa S, Ohno H . Selection
of an aptamer against mouse GP2 by SELEX.Cell Struct Funct .2014;39(1):23-9. Epub 2013 Dec 12.
2013年
Furusawa Y, Obata Y, Fukuda S, Endo TA, Nakato G, Takahashi D, Nakanishi
Y, Uetake C, Kato K, Kato T, Takahashi M, Fukuda NN, Murakami S, Miyauchi
E, Hino S, Atarashi K, Onawa S, Fujimura Y, Lockett T, Clarke JM, Topping
DL, Tomita M, Hori S, Ohara O, Morita T, Koseki H, Kikuchi J, Honda K,
Hase K , Ohno H . Commensal microbe-derived butyrate induces the differentiation
of colonic regulatory T cells.
Nature .2013 Dec 19;504(7480):446-50. doi: 10.1038/nature12721. Epub 2013 Nov 13.
Hase K, Nakatsu F, Ohmae M, Sugihara K, Shioda N, Takahashi D, Obata Y,
Furusawa Y, Fujimura Y, Yamashita T, Fukuda S, Okamoto H, Asano M, Yonemura
S, Ohno H .AP-1B-mediated protein sorting regulates polarity and proliferation
of intestinal epithelial cells in mice.
Gastroenterology.2013 Sep;145(3):625-35
Mandai Y, Takahashi D, Hase K, Obata Y, Furusawa Y, Ebisawa M, Nakagawa
T, Sato T, Katsuno T, Saito Y, Shimaoka T, Yokosuka O, Yokote K, Ohno H. Distinct
Roles for CXCR6+ and CXCR6- CD4+ T Cells in the Pathogenesis of Chronic
Colitis.PLoS One.2013 Jun 19;8(6):e65488
2012年
Nakato G , Hase K, Suzuki M, Kimura M, Ato M, Hanazato M, Tobiume M, Horiuchi
M, Atarashi R, Nishida N, Watarai M, Imaoka K, Ohno H. Cutting Edge:Brucella
abortus Exploits a Cellular Prion Protein on Intestinal M Cells as an Invasive
Receptor.
J Immunol .2012 Jul 6. [Epub ahead of print]
Kanaya T , Hase K, Takahashi D, Fukuda S, Hoshino K, Sasaki I, Hemmi H,
Knoop KA, Kumar N, Sato M, Katsuno T, Yokosuka O, Toyooka K, Nakai K, Sakamoto
A, Kitahara Y, Jinnohara T, McSorley SJ, Kaisho T, Williams IR, Ohno H.
The Ets transcription factor Spi-B is essential for the differentiation
of intestinal microfold cells.
Nat Immunol.2012 Jun 17. doi: 10.1038/ni.2352. [Epub ahead of print]
Obata Y , Takahashi D, Ebisawa M, Kakiguchi K, Yonemura S, Jinnohara T,
Kanaya T, Fujimura Y, Ohmae M, Hase K, Ohno H. Epithelial cell-intrinsic
Notch signaling plays an essential role in the maintenance of gut immune
homeostasis.
J Immunol. 2012 Mar 1;188(5):2427-36. Epub 2012 Jan 25.
2011年
Nakanishi Y, Fukuda S, Chikayama E, Kimura Y, Ohno H, Kikuchi J.
Dynamic Omics Approach Identifies Nutrition-Mediated Microbial Interactions.
J Proteome Res.2011 Feb 4;10(2):824-836. Epub 2010 Dec 20.
Fukuda S, Toh H, Hase K, Oshima K, Nakanishi Y, Yoshimura K, Tobe T, Clarke
JM, Topping DL, Suzuki T, Taylor TD, Itoh K, Kikuchi J, Morita H, Hattori
M, Ohno H.
Bifidobacteria can protect from enteropathogenic infection through production
of acetate.
Nature.2011 Jan 27;469(7331):543-7.
Ito M, Kitamura H, Kikuguchi , Hase K, Ohno H, Ohara O.
SP600125 inhibits cap-dependent translation independently of the c-Jun
N-terminal kinase pathway.
Cell Struct Funct.2011 Jan 20.
2010年
Morita H, Nakano A, Onoda H, Toh H, Oshima K, Takami H, Murakami M, Fukuda
S, Takizawa T, Kuwahara T, Ohno H, Tanabe S, Hattori M. Bifidobacterium
kashiwanohense sp. nov., isolated from healthy infant faeces.
Int J Syst Evol Microbiol.2010 Dec 10.
Shima H, Takatsu H, Fukuda S, Ohmae M, Hase K, Kubagawa H, Wang JY, Ohno
H.
Identification of TOSO/FAIM3 as an Fc receptor for IgM.
Int Immunol. 2010 Mar;22(3):149-56. Epub 2009 Dec 30.
Date Y, Nakanishi Y, Fukuda S, Kato T, Tsuneda S, Ohno H, Kikuchi J.
New monitoring approach for metabolic dynamics in microbial ecosystems
using stable-isotope-labeling technologies.J Biosci Bioeng.2010 Jul;110(1):87-93. Epub 2010 Jan 27.
Ohno H, Hase K, Kimura S
M-Sec: Emerging secrets of tunneling nanotube formation.
Commun Integr Biol.2010 May;3(3):231-3.
2009年
Hase K, Kimura S, Takatsu H, Ohmae M, Kawano S, Kitamura H, Ito M, Watarai
H, Hazelett CC, Yeaman C, Ohno H.
M-Sec promotes membrane nanotube formation by interacting with Ral and
the exocyst complex.
Nat Cell Biol .2009 Dec;11(12):1427-32. Epub 2009 Nov 22.
Hase K, Kawano K, Nochi T, Pontes GS, Fukuda S, Ebisawa M, Kadokura K,
Tobe T, Fujimura Y, Kawano S, Yabashi A, Waguri S, Nakato G, Kimura S,
Murakami T, Iimura M, Hamura K, Fukuoka S, Lowe AW, Itoh K, Kiyono H, Ohno
H.
Uptake through glycoprotein 2 of FimH(+) bacteria by M cells initiates
mucosal immune response.
Nature.2009 Nov 12;462(7270):226-30.
Nakato G, Fukuda S, Hase K, Goitsuka R, Cooper MD, Ohno H.
New approach for m-cell-specific molecules screening by comprehensive transcriptome
analysis.
DNA Res .2009 Aug;16(4):227-35.
Fukuda, S., Nakanishi, Y., Chikayama, E., Ohno, H. , Hino, T., Kikuchi,
J.
Evaluation and characterization of bacterial metabolic dynamics with a
novel profiling technique, real-time metabolotyping.
PLoS ONE4: e4893, 2009
Sugiura, Y., Nakatsu, F., Hiroyasu, K., Ishi, A., Hirose, S., Okada, M.,
Jibiki, I, Ohno, H., Kaneko, S., Ugawa, Y.
Lack of potassium current in W309R mutant KCNQ3 channel causing benign
familial neonatal convulsions (BFNC).
Epilepsy Res.84 (1:): 82-85, 2009
2008年
Zhu, G., Okada, M., Yoshida, S., Ieno, S., Mori, F., Takahara, T., Saito,
RR., Miura, Y., Kishi, A., Tomiyama, M., Sato, A., Kojima, T., Fukuma,
G., Wakabayashi, K., Hase, K., Ohno, H ., Kijima, H., Takano, Y., Mitsudome,
A., Kaneko, S., Hirose, S.
Rats harboring S284L Chrna4 mutation show attenuation of synaptic and extrasynaptic
GABAergic transmission and exhibit the nocturnal frontal lobe epilepsy
phenotype.
J. Neurosci.28 (8): 12465-12476, 2008.
Hase K, Takahashi D, Ebisawa M, Kawano S, Itoh K, Ohno H.
Activation-induced cytidine deaminase deficiency causes organ-specific
autoimmune disease.
PLoS ONE .2008 Aug 21; 3 ( 8 ): e3033.
Kamijuku, H., Nagata, Y., Jiang, X., Ichinohe, T., Tashiro, T., Mori, K.,
Taniguchi, M., Hase, K., Ohno, H. , Shimaoka, T., Yonehara, S., Odagiri,
T., Tahiro, M., Sata, T., Hasegawa, H., Seino, K-i.
Mechanism of NKT cell activation by intranasal coadministration of a -galactosylceramide,
which can induce cross-protection against influenza.
Mucosal Immunol.1(3): 208-218, 2008
Terahara, K.*, Yoshida, M.*, Igarashi, O., Nochi, T., Pontes, G. S., Hase,
K., Ohno, H. , Kurokawa, S., Mejima, M., Takayama, N., Yuki, Y., Lowe,
A. W., Kiyono, H.
Comprehensive gene expression profiling of Peyer's patch M cells, villous
M-like cells, and intestinal epithelial cells.
J. Immunol.180 (12): 7840-7846, 2008(*First two authors contributed equally to this
work.)
Morita, H., Toh, H., Fukuda, S., Horikawa, H., Oshima, K., Suzuki, T.,
Murakami, M., Hisamatsu, S., Kato, Y., Takizawa, T., Fukuoka, H., Yoshimura,
T., Itoh, K., O'Sullivan, D. J., McKay, L. L., Ohno, H. , Kikuchi, J.,
Masaoka, T., Hattori, M.
Comparative genome analysis of Lactobacillus reuteri and Lactobacillus
fermentum reveal a genomic island for reuterin and cobalamin production.
DNA Res.15 (3): 151-161, 2008
Misawa, H., Fujigaya, H., Nishimura, T., Moriwaki, Y., Okuda, T., Kawashima,
K., Nakata, K., Ruggiero, A. M., Blakely, R. D., Nakatsu, F., Ohno, H .
Aberrant trafficking of the high-affinity choline transporter in AP-3-deficient
mice.
Eur. J. Neurosci.27 (12): 3109-3117, 2008
2007年
Kawano K, Ebisawa M, Hase K, Fukuda S, Hijikata A, Kawano S, Date Y, Tsuneda
S, Itoh K, Ohno H.
Psg18 is specifically expressed in follicle-associated epithelium.
Cell Struct Funct .2007; 32 ( 2 ): 115-26 . Epub 2007 Nov 5.
Murakami T, Chen X, Hase K, Sakamoto A, Nishigaki C, Ohno H.
Splenic CD19-CD35+B220+ cells function as an inducer of follicular dendritic
cell network formation.
Blood .2007 Aug 15; 110 ( 4 ): 1215-24 . Epub 2007 May 22.
Huang, M. C., Okada, M., Nakasu, F., Oguni, H., Ito, M., Morita, K., Nagafuji,
H., Hirose, S., Sasaki, Y., Kaneko, S., Ohno, H. , Kojima, T.
Mutation screening of AP3M2 in Japanese epilepsy patients.
Brain Dev.29(8): 462-467, 2007
Hijikata, A., Kitamura, H., Kimura, Y., Yokoyama, R., Aiba, Y., Bao, Y.,
Fujita, S., Hase, K., Hori, S., Ishii, Y., Kanagawa, O., Kawamoto, H.,
Kawano, K., Koseki, H., Kibo, M., Kurita-Miki, A., Kurosaki, T., Masuda,
K., Nakata, M., Oboki, K., Ohno, H ., Okamoto, M., Okayama, Y., O-Wang,
J., Saito, H., Saito, T., Sakuma, M., Sato, K., Seino, K., Setoguchi, R.,
Tamura, Y., Tanaka, M., Taniguchi, M., Taniuchi, I., Teng, A., Watanabe,
T., Watarai, H., Yamasaki, S., Ohara, O.
Construction of an open-access database that integrates cross-reference
information from the transcriptome anda proteome of immune cells.
Bioinformatics23(21): 2934-2941, 2007
2006年
Takatsu H, Hase K, Ohmae M, Ohshima S, Hashimoto K, Taniura N, Yamamoto
A, Ohno H.
CD300 antigen like family member G: A novel Ig receptor like protein exclusively
expressed on capillary endothelium.Biochem Biophys Res Commun .2006 Sep 15; 348 ( 1 ): 183-91 . Epub 2006 Jul 21.
Fujimoto M, Takatsu H, Ohno H.
CMRF-35-like molecule-5 constitutes novel paired receptors, with CMRF-35-like
molecule-1, to transduce activation signal upon association with FcRgamma.
Int Immunol .2006 Oct; 18 ( 10 ): 1499-508 . Epub 2006 Aug 28.
Hase K, Murakami T, Takatsu H, Shimaoka T, Iimura M, Hamura K, Kawano K,
Ohshima S, Chihara R, Itoh K, Yonehara S, Ohno H.
The membrane-bound chemokine CXCL16 expressed on follicle-associated epithelium
and M cells mediates lympho-epithelial interaction in GALT.
J Immunol .2006 Jan 1; 176 ( 1 ): 43-51.
Takano-Maruyama, M., Hase, K., Fukamachi, H., Kato, Y., Koseki, H., Ohno,
H .
Foxl1-deficient mice exhibit aberrant epithelial cell positioning due to
dysregulated EphB/EphrinB in the small intestine.Am. J. Physiol. Gastrointest. Liver Physiol.291(1): G163-G170, 2006
Luo, H., Nakatsu, F., Furuno, A., Kato, H., Yamamoto, A., Ohno, H .
Visualization of the post-Golgi trafficking of multi-photon photoactivated
transferrin receptors.
Cell Struct. Funct .31: 63-75, 2006
2005年
Mitsunari, T. Nakatsu, F., Shioda, N., Love, P.E., Grinberg, A., Bonifacino,
J.S., Ohno, H.
Clathrin adaptor AP-2 is essential for early embryonal development.
Mol. Cell. Biol.25 (21): 9318-9323, 2005.
Hase, K., Ohshima, S., Kawano, K., Hashimoto, N., Matsumoto, K., Saito,
H., Ohno, H.
Distinct gene expession profiles characterize cellular phenotypes of follicle-associated
epithelium and M cells.
DNA Res.12 (2): 127-137, 2005.
2004年
Nakatsu F, Okada M, Mori F, Kumazawa N, Iwasa H, Zhu G, Kasagi Y, Kamiya
H, Harada A, Nishimura K, Takeuchi A, Miyazaki T, Watanabe M, Yuasa S,
Manabe T, Wakabayashi K, Kaneko S, Saito T, Ohno H.
Defective function of GABA-containing synaptic vesicles in mice lacking
the AP-3B clathrin adaptor.
J Cell Biol.167(2):293-302.2004.
Kato, Y., Fukamachi, H., Takano-Maruyama, M., Aoe, T., Murahashi, Y., Horie,
S., Suzuki, Y., Saito, Y., Koseki, H., Ohno H.
Reduction of SNAP25 in acid secretion defect of Foxl1 -/- g a stric parietal
cells.
Biochem. Biophys. Res. Commun.320(3): 766-772, 2004.
Ito, M., Iidawa, S., Izuka, M., Haito, S., Segawa, H., Kuwahata, M., Ohkido,
I., Ohno, H ., Miyamoto K.
Intreaction of a farnesylated protein with renal type IIa Na/Pi cotransporter
in response to parathyroid hormone and dietary phosphate.
Biochem. J.377: 607-616, 2004 .
Yoshimura, S., Yamamoto, A., Misumi, Y., Sohda, M., Barr, F. A., Fujii,
G., Shakoori, A., Ohno, H. , Mihara, K., Nakamura, N.
Dynamics of Golgi matrix proteins after the blockage of ER to Golgi transport.
J. Biochem.135(2): 201-216, 2004.
2003年
Shakoori, A., Fujii, G., Yoshimura, S., Kitamura, M., Nakayama, K., Ito,
T., Ohno, H. , Nakamura, N.
Identification of a five-pass transmembrane protein family localizing in
the Golgi apparatus and the ER.
Biochem. Biophys. Res.Commun.312(3): 850-857, 2003.
Ohno, H.
Membrane traffic in the post-Golgi network: toward a better understanding
of the higher order functioning systems.
Cell Struct. Funct.28: 396-397, 2003.
Nakatsu, F., Ohno, H.
The adaptor protein complex: A key regulators of protein sorting in post-Golgi
network.
Cell Struct. Funct.28: 419-429, 2003.
2002年
Nishimura, K., Nakatsu, F., Kashiwagi, K., Ohno, H ., Saito, T., Igarashi
K.
Essential role of S-adenosylmethionine decarboxylase in mouse embryonic
development.
Genes Cells7(1):41-47, 2002
Nakamichi, N., Ohno, H , Kuramoto, N., Yoneda, Y.
Dual mechanisms of Ca 2+ increases elicited by N-methyl-D-aspartate in
immature and mature cultured cortical neurons.J. Neurosci. Res.67(2): 275-283, 2002.
Eskelinen, E.-L., Meyer, C., Ohno H., von Figura, K., Schu, P.
The polarized epithelia specific m 1B-adaptin complements m 1A-deficiency
in fibroblasts.
EMBO Report3(5): 471-477, 2002 .
Sugimoto, H., Sugahara, M., Folsch, H., Koide, Y., Nakatsu, F., Tanaka,
N., Nishimura, T., Furukawa, M., Mullins, C., Nakamura, N., Mellman, I.,
Ohno, H.
Differential recognition of tyrosine-based basolateral signals by the AP-1B
subunit m 1B in polarized epithelial cells.
Mol. Biol. Cell13(7): 2374-2382, 2002
Nakamichi N, Ohno H , Nakamura Y, Hirai T, Kuramoto N, Yoneda Y.
Blockade by ferrous iron of Ca2+ influx through N-methyl-d-aspartate receptor
channels in immature cultured rat cortical neurons.
J . Neurochem.83(1): 1-11, 2002
Fu kamachi, K., Matsuoka, Y., Ohno, H ., Hamaguchi, T., Tsuda, H.
Neuronal leucine-rich repeat protein-3 amplifies MAP kinase activation
by EGF through a carboxyl-terminal region containing endocytosis motifs.
J. Biol. Chem.277(46): 43549- 435 52 , 2002
Tabuchi, M., Tanaka, N., Nishida-Kitayama, J., Ohno, H., Kishi, F.
Alternative splicing regulates the subcellular localization of divalent
metal ion transporter 1 isoforms.
Mol. Biol. Cell 13(12): 4371- 43 87 , 2002
2001年
Arase, H., Suenaga, T., Arase, N., Kimura, Y., Ito, K., Shiina, R., Ohno,
H . and Saito, T.
Negati v e regulation of expression and function of Fc g RIII by CD3 z
in murine NK cells.
J. Immunol .166(1): 21-25, 2001.
Aguilar, R. C., Boehm, M., Gorshkova, I., Crouch, R. J., Tomita, K., Saito,
T., Ohno, H.
and Bonifacino, J. S.: Signal-binding specificity of the m 4 subunit of
the adaptor protein complex, AP-4.
J. Biol. Chem. 276(16): 13145-13152, 2001.
Tomita, K., Saijo, K., Yamasaki, S., Iida, T., Nakatsu, F., Arase, H.,
Ohno, H ., Shirasawa, T., Kuriyama, T., O'Shea, J. J. and Saito, T.
Cytokine-independent Jak3 activation upon TCR stimulation through direct
association of Jak3 and the TCR complex.
J. Biol. Chem .276(27): 25378-25385, 2001.
Ohka, S., Ohno, H ., Tohyama, K., and Nomoto, A.
Basolateral sorting of human poliovirus receptor a involves an interaction
with the m 1B subunit of the clathrin adaptor complex in polarized epithelial
cells.
Biochem. Biophys. Res. Commun.287(4):941-948, 2001.
Blumstein , J. , Faundez, V., Nakatsu, F., Saito, T., Ohno, H ., Kelly,
R. B.
The neuronal form of AP-3 is required for synaptic vesicle formation from
endosomes.
J. Neurosci.21(20): 8034-8042, 2001 .
Yoshimura, S., Nakamura, N., Barr, F. A., Misumi, Y., Ikehara, Y., Ohno,
H ., Sakaguchi, M., Mihara, K.
Direct targeting of GM130, a cis-Golgi matrix protein, to the Golgi apparatus.
J. Cell Sci .114(Pt22): 4105-4115, 2001.
Uekita, T., Itoh, Y., Tana, I., Ohno, H. , Seiki, M.
Cytoplasmic tail dependent internalization of membrane-type 1 matrix metalloproteinase
(MT1-MMP) is important for its inva s ion-promoting activity .
J. Cell Biol.155(7): 1345-1356, 2001.
2000年
Nakatsu, F., Sakuma, M., Matsuo, Y., Arase, H., Yamasaki, S., Nakamura,
N., Saito, T., Ohno, H .
A di-leucine signal in the ubiquitin moiety: possible involvement in ubiquitination-mediated
endocytosis.
J. Biol. Chem.275(34): 26213-26219, 2000.
Kuno, K., Okada, Y., Kawashima, H., Nakamura, H., Miyasaka, M., Ohno, H
., Matsushima, K.
ADAMTS-1 cleaves a cartilage proteoglycan, aggrican.
FEBS Lett. 478(3): 241-245, 2000.
Okazaki, Y., Ohno, H ., Takase, K., Ochiai, T. and Saito, T.
Cell surface expression of calnexin, a molecular chaperone in the endoplasmic
reticulum.
J. Biol. Chem .275(46): 35751-35758, 2000.
Iida, T., Ohno, H ., Nakaseko, C., Sakuma, M., Takeda-Ezaki, M., Arase,
H., Kominami, E., Fujisawa, T. and Saito, T.
Regulation of cell surface expression of CTLA-4 by secretion of CTLA-4-containing
lysosomes upon activation of CD4+ T cells.
J. Immunol .165(9): 5062-5068, 2000.
1999年
Ohno, H ., Tomemori, T., Nakatsu, F., Okazaki, Y., Aguilar, R. C., Foelsch,
H., Mellman, I., Saito, T., Shirasawa, T., Bonifacino, J.S.
m 1B: a novel adaptor medium chain expressed in polarized epithelial cells.
FEBS Lett.449(2-3): 215-220, 1999.
Wild, M. K., Cambiaggi, A., Brown, M. H., Davies, E. A., Ohno, H. , Saito,
T., van der Merwe, P. A.
Dependence of T cell antigen recognition on the dimensions of and accessory
receptor-ligand complex.
J. Exp. Med.190(1): 31-41 , 1999.
Nakaseko C, Miyatake S, Iida T, Hara S, Abe R, Ohno H , Saito T.
Cytotoxic T lymphocyte antigen 4 (CTLA-4) engagement delivers an inhibitory
signal through the membrane-proximal region in the absence of the tyrosine
motif in the cytoplasmic tail.
J. Exp. Med.190(6): 765-774, 1999.
Folsch, H., Ohno, H. , Bonifacino, J. S., Mellman, I.
A novel clathrin adaptor complex mediates basolateral targeting in polarized
epithelial cells.
Cell99(2): 189-198, 1999.
Watanabe, N., Akikusa, B., Park, S. Y., Ohno, H ., Fossati, L., Vecchietti,
G., Gessner, J. E., Schmidt, R. E., Verbeek, J. S., Ryffel, B., Iwamoto,
I., Izui, S., Saito, T.
Mast cells induce autoantibody-mediated vasculitis syndrome through tumor
necrosis factor production upon triggering Fc g receptors.
Blood94(11): 3855-3863, 1999.
Nakatsu, F., Kadohira, T., Gilbert, D. J., Jenkins, N. A., Kakuda, H.,
Copeland, N. G., Saito, T., Ohno, H.
Genomic structure and chromosomal mapping of the genes encoding clathrin-associated
adaptor medium chains m 1A (Ap1m1) and m 1B (Ap1m2). Cytogenet.Cell Genet.87(1-2): 53-58, 1999.